Pathophysiological characterization of patients with acute myocardial infarction with STsegment elevation

Authors

  • Annie Gil Landave Universidad de Ciencias Médicas de Santiago de Cuba, Cuba
  • Odalis Querts Méndez Universidad de Ciencias Médicas de Santiago de Cuba, Cuba
  • Maidilis Beltrán Moret Universidad de Ciencias Médicas de Santiago de Cuba, Cuba
  • Yusnay Robert Ramos Universidad de Ciencias Médicas de Santiago de Cuba, Cuba

Keywords:

Acute myocardial infarction, ischemic heart disease, ST segment elevation, pathophysiological characteristics

Abstract

Introduction: Acute myocardial infarction (AMI) represents the most significant manifestation of ischemic heart disease,
which occurs when acute coronary occlusion occurs, causing myocardial necrosis as a result of severe ischemia. Materials
and Methods: A retrospective cross-sectional descriptive study was carried out in 765 patients with acute myocardial
infarction with ST segment elevation in the period from 2018 to 2022 with the objective of describing the pathophysiological
characteristics of Acute Myocardial Infarction in patients with elevation of the segment. ST. The data were obtained from
the medical records. The variables were studied: age, sex, modifiable coronary risk factors, evaluation of nutritional status,
topography, complications, diagnostic criteria and death. Descriptive statistics (absolute and relative frequency) were used to process the information. Results: The male population over 77 years of age was more likely to die from cardiovascular
diseases. The most relevant coronary risk factor found was high blood pressure. The most frequent location was on the
lower face, hemodynamic complications prevailed in the studied population and clinical and electrocardiographic criteria
were the most used to obtain the diagnosis of the patients. Discussion: Cuban researchers such as Molina et al. made
several contributions, since they found that patients with systolic blood pressure equal to or greater than 140 mmHg
had a three-fold increased risk of suffering from cardiovascular disease. It has been shown that 50.0% of hypertensive
patients suffer from chest pain and that the possibility of a major coronary accident is 3 times higher in these patients.
Conclusions: Men are the most affected by acute myocardial infarction, as well as high blood pressure along with smoking
constituted the most relevant coronary risk factors, the latter triggers the release of catecholamines causing damage to the
endothelium, increases the coronary tone with spasm and produces coagulation disorders.

References

Colectivo de autores. (2020). Guía ESC/EAS 2019 sobre el tratamiento de las dislipemias. European Heart Journal. 41, 111-188. https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehz455#supplementary-data

Cordero A, et al. (2012). Mortalidad a largo plazo y reingreso hospitalario tras infarto agudo de miocardio, un estudio de seguimiento de ocho años. Rev Esp Cardiol. 65(5), 414-420. https://www.revespcardiol.org/en-mortalidadlargo-plazo-reingreso-hospitalario-articulo-S0300893211008025

Fernández-Ortiz. A. (2018). ¿Qué es el infarto agudo de miocardio? https://www.fbbva.es/microsites/salud_cardio/fbbva_libroCorazon_ficha_28.html.

Franco, M. R., Sainz, B., Ramos, B. y Frías, J. A. (2015). Caracterización de pacientes con infarto agudo de miocardio con elevación del segmento ST. Rev Cub Cardiol Cir Cardiovasc. 21(1), 16-23. https://www.medigraphic.com/pdfs/cubcar/ccc-2015/ccc151d.pdf

Kristian K, Alpert JS, Jaffe AF, Chaitman BR, Bax JJ, Morrow DA, White HD. (2019). Consenso ESC 2018 sobre la cuarta definición universal del infarto de miocardio. Rev Esp Cardiol. 2019; 72 (1):72. e1-e27.

Martínez A, Sainz BA, Ramos B, Pacheco E, Zorio BY, Castañeda G. (2017). Infarto agudo con elevación del ST en el servicio de urgencias del Instituto de Cardiología. Rev Cuban Cardiol, 23(1). http://revcardiologia.sld.cu/index.php/revcardiologia/article/view/677/pdf_76

Mirvis DM, Goldberger AL. (2019). Electrocardiography. En: Braunwald‘s Heart Disease. 11 ed. Elsevier Saunders. 135.

Noya, M. E. y Moya, N. L. Roca Goderich. (2017). Temas de Medicina Interna I. (5.ª ed.). Editorial Ciencias Médicas.

Ortega Torres YY, Armas Rojas NB, Dueñas Herrera A, De la Noval R, Acosta Rodríguez M. (2015). Prevención primaria de la cardiopatía isquémica. Aspectos de interés. Rev Cub. de Cardiol; 21(1). http://www.revcardiologia.sld.cu/index.php/revcardiologia/article/view/566

Sánchez VM, Bosch C, Sánchez TM y González JC. (2014). Morbilidad y mortalidad por Infarto Agudo de Miocardio. MEDISAN, 18(4), 516-522. http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192014000400008&lng=es

Published

2023-12-20

How to Cite

Gil Landave, A., Querts Méndez, O., Beltrán Moret, M., & Robert Ramos, Y. (2023). Pathophysiological characterization of patients with acute myocardial infarction with STsegment elevation. Maestro Y Sociedad, 449–459. Retrieved from https://maestroysociedad.uo.edu.cu/index.php/MyS/article/view/6297

Issue

Section

Número Especial

Most read articles by the same author(s)